SCHEMBL21834813

SCHEMBL21834813

Cc1cc(C(Cc2ccc(I)cc2)NC(=O)OC(C)(C)C)nc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRB P23467 4/20 0.46
KMT2A Q03164 3/20 0.44
RAB9A P51151 2/20 0.44
MEN1 O00255 2/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 5/20 0.43
LMNA P02545 4/20 0.43
HPGD P15428 4/20 0.43
HTT P42858 4/20 0.43
NPSR1 Q6W5P4 4/20 0.43
XBP1 P17861 2/20 0.43
JAK2 O60674 2/20 0.43
S1PR4 O95977 1/20 0.43
HSP90AA1 P07900 1/20 0.43
THRB P10828 1/20 0.43
PKM P14618 3/20 0.43
TSHR P16473 3/20 0.43
HSD17B10 Q99714 2/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28840049 0.93 ALDH1A1 (0.49) PTPRBKMT2ARAB9AMEN1NPC1
SCHEMBL28128780 0.89 PTPRB (0.45) PTPRBKMT2ARAB9AMEN1NPC1
SCHEMBL28128781 0.81 ALDH1A1 (0.48) PTPRBKMT2ARAB9AMEN1NPC1
SCHEMBL21848520 0.80 ALDH1A1 (0.51) KMT2ARAB9AMEN1NPC1GAA
SCHEMBL21848540 0.80 MEN1 (0.46) KMT2ARAB9AMEN1NPC1GAA
SCHEMBL21848543 0.78 GPR55 (0.47) KMT2ARAB9AMEN1ALDH1A1HPGD
SCHEMBL21834803 0.78 GPR55 (0.47) KMT2ARAB9AMEN1ALDH1A1HPGD
SCHEMBL21848423 0.78 GPR55 (0.47) KMT2ARAB9AMEN1ALDH1A1HPGD
SCHEMBL28459551 0.75 GRM2 (0.39) KMT2AMEN1NPC1GAAALDH1A1
SCHEMBL21848465 0.73 MAPT (0.47) KMT2ARAB9AMEN1NPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020063399-A1 METHOD FOR LIGHT-INDUCED DECARBOXYLATION COUPLING OF ACTIVE CARBOXYLIC ACID ESTER UNDER NON-METAL CATALYSIS 中国科学技术大学 2020-04-02 WO disclosed
WO-2020063399-A1 METHOD FOR LIGHT-INDUCED DECARBOXYLATION COUPLING OF ACTIVE CARBOXYLIC ACID ESTER UNDER NON-METAL CATALYSIS 中国科学技术大学 2020-04-02 WO disclosed