SCHEMBL21848520

SCHEMBL21848520

CSCCC(NC(=O)OC(C)(C)C)c1cc(C)c2ccccc2n1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
TSHR P16473 4/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
LMNA P02545 4/20 0.51
HSD17B10 Q99714 2/20 0.51
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
FPR1 P21462 3/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21848424 0.88 ALDH1A1 (0.49) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL21834844 0.85 FPR1 (0.47) ALDH1A1TSHRKMT2ALMNAFPR1
SCHEMBL21834843 0.85 FPR1 (0.47) ALDH1A1TSHRKMT2ALMNAFPR1
SCHEMBL28840049 0.84 ALDH1A1 (0.49) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL21848540 0.82 MEN1 (0.46) MEN1KMT2ALMNAHSD17B10NPC1
SCHEMBL21834813 0.80 PTPRB (0.46) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL21834812 0.79 MAPT (0.47) MEN1KMT2ANPC1GAARAB9A
SCHEMBL21848465 0.79 MAPT (0.47) MEN1KMT2ANPC1GAARAB9A
SCHEMBL28329433 0.75 CTSK (0.48) ALDH1A1MEN1KMT2ANPC1GAA
SCHEMBL28128781 0.72 ALDH1A1 (0.48) ALDH1A1TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020063399-A1 METHOD FOR LIGHT-INDUCED DECARBOXYLATION COUPLING OF ACTIVE CARBOXYLIC ACID ESTER UNDER NON-METAL CATALYSIS 中国科学技术大学 2020-04-02 WO disclosed