SCHEMBL21848423

SCHEMBL21848423

CC(=O)N[C@H](Cc1ccccc1)c1cc(C)c2ccccc2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.47
CTRB1 P17538 4/20 0.46
TACR3 P29371 2/20 0.46
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
APEX1 P27695 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
METAP1 P53582 1/20 0.43
PRNP P04156 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
TACR1 P25103 1/20 0.42
OPRM1 P35372 1/20 0.42
OPRD1 P41143 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21834803 1.00 GPR55 (0.47) GPR55CTRB1TACR3ALDH1A1SMN1; SMN2
SCHEMBL21848543 1.00 GPR55 (0.47) GPR55CTRB1TACR3ALDH1A1SMN1; SMN2
SCHEMBL28840049 0.84 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2HPGDMEN1MAPT
SCHEMBL21834844 0.82 FPR1 (0.47) ALDH1A1HPGDPOLBMAPTKMT2A
SCHEMBL21834843 0.82 FPR1 (0.47) ALDH1A1HPGDPOLBMAPTKMT2A
SCHEMBL28488694 0.80 PRNP (0.50) TACR3ALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL28488696 0.80 PRNP (0.50) TACR3ALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL21834846 0.78 PRNP (0.51) TACR3ALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL21834845 0.78 PRNP (0.51) TACR3ALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL21834813 0.78 PTPRB (0.46) ALDH1A1SMN1; SMN2HPGDMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180576-B Method for photo-inducing nonmetal enantioselectively catalyzing heterocyclic aromatic hydrocarbon minisci reaction 中国科学技术大学 2020-08-25 CN disclosed
WO-2020063399-A1 METHOD FOR LIGHT-INDUCED DECARBOXYLATION COUPLING OF ACTIVE CARBOXYLIC ACID ESTER UNDER NON-METAL CATALYSIS 中国科学技术大学 2020-04-02 WO disclosed