Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099538 | 0.83 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL31168163 | 0.83 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL5551100 | 0.83 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL10890112 | 0.83 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL7190691 | 0.81 | TDP1 (0.50) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL465790 | 0.79 | CYP3A4 (0.47) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL3591773 | 0.79 | CYP3A4 (0.52) | CYP3A4TRPA1TDP1MEN1LMNA | |
| Water SCHEMBL27519980 | 0.79 | TDP1 (0.48) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL15528637 | 0.79 | CYP3A4 (0.47) | CYP3A4TRPA1TDP1MEN1LMNA | |
| SCHEMBL29395383 | 0.77 | CYP3A4 (0.64) | CYP3A4TRPA1TDP1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222314-B2 | Phenyl isocyanate-based urethane acrylates, processes for producing and methods of using the same | BAYER MATERIALSCIENCE AG (DE) | 2012-07-17 | — | — | US | claimed |
| EP-2154129-A1 | Phenylisocyanate based urethanacrylate with high refraction index | Bayer MaterialScience AG (DE) | 2010-02-17 | — | — | EP | claimed |
| EP-2154128-A1 | Phenylisocyanate based urethanacrylates with high refraction index | Bayer MaterialScience AG (DE) | 2010-02-17 | — | — | EP | claimed |
| US-20100036013-A1 | PHENYL ISOCYANATE-BASED URETHANE ACRYLATES, PROCESSES FOR PRODUCING AND METHODS OF USING THE SAME | BAYER MATERIALSCIENCE AG (DE) | 2010-02-11 | — | — | US | claimed |
| CN-101704773-B | Phenyl isocyanate-based urethane acrylates, processes for making and methods of using the same | BAYER MATERIALSCIENCE AG | 2014-03-05 | — | — | CN | disclosed |
| US-8222314-B2 | Phenyl isocyanate-based urethane acrylates, processes for producing and methods of using the same | BAYER MATERIALSCIENCE AG (DE) | 2012-07-17 | — | — | US | disclosed |
| EP-2342249-A1 | PREPOLYMER-BASED POLYURETHANE FORMULATIONS FOR PRODUCING HOLOGRAPHIC MEDIA | Bayer MaterialScience AG (DE) | 2011-07-13 | — | — | EP | disclosed |
| CN-101704773-A | Phenyl isocyanate-based urethane acrylates, processes for making and methods of using the same | BAYER MATERIALSCIENCE AG | 2010-05-12 | — | — | CN | disclosed |
| WO-2010037496-A1 | PREPOLYMER-BASED POLYURETHANE FORMULATIONS FOR PRODUCING HOLOGRAPHIC MEDIA | BAYER MATERIALSCIENCE AG (DE) | 2010-04-08 | — | — | WO | disclosed |
| EP-2154129-A1 | Phenylisocyanate based urethanacrylate with high refraction index | Bayer MaterialScience AG (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-2154128-A1 | Phenylisocyanate based urethanacrylates with high refraction index | Bayer MaterialScience AG (DE) | 2010-02-17 | — | — | EP | disclosed |
| US-20100036013-A1 | PHENYL ISOCYANATE-BASED URETHANE ACRYLATES, PROCESSES FOR PRODUCING AND METHODS OF USING THE SAME | BAYER MATERIALSCIENCE AG (DE) | 2010-02-11 | — | — | US | disclosed |
| US-6653295-B2 | Protease inhibitor; viricide | BRISTOL-MYERS SQUIBB COMPANY | 2003-11-25 | — | — | US | disclosed |
| US-20030064962-A1 | Inhibitors of hepatitis C virus NS3 protease | BRISTOL-MYERS SQUIBB COMPANY (FORMERLY D/B/A DUPONT PHARMACEUTICALS COMPANY) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030064962-A1 | Inhibitors of hepatitis C virus NS3 protease | PRSS1, SERPINB1, SPINT2 | CYP3A4 135/4885TRPA1 4380/4885TDP1 1691/4885 |
| US-20100036013-A1 | PHENYL ISOCYANATE-BASED URETHANE ACRYLATES, PROCESSES FOR PRODUCING AND METHODS OF USING THE SAME | GRHPR, CBR1, C1S | CYP3A4 783/4885TRPA1 307/4885TDP1 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.