Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 8/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529476 | 0.80 | SLC6A5 (0.54) | TLR2MMP2MMP9FOLH1SLC6A5 | |
| SCHEMBL30901213 | 0.80 | SLC6A5 (0.54) | TLR2MMP2MMP9FOLH1SLC6A5 | |
| SCHEMBL6152838 | 0.76 | MMP2 (0.45) | TLR2MMP2MMP9FOLH1 | |
| SCHEMBL5840486 | 0.76 | MMP2 (0.45) | TLR2MMP2MMP9FOLH1 | |
| SCHEMBL8664220 | 0.76 | MMP2 (0.45) | TLR2MMP2MMP9FOLH1 | |
| SCHEMBL2778592 | 0.73 | TLR2 (0.43) | TLR2MMP2MMP9FOLH1ALDH1A1 | |
| Phthalic Acid SCHEMBL28116915 | 0.73 | ALDH1A1 (0.54) | ALDH1A1CA12CA9 | |
| SCHEMBL29448214 | 0.72 | CPB2 (0.53) | TLR2MMP2MMP9 | |
| SCHEMBL136079 | 0.72 | FOLH1 (0.59) | FOLH1ALDH1A1CA2CA12CA1 | |
| Benzene SCHEMBL8597142 | 0.72 | FOLH1 (0.59) | FOLH1ALDH1A1CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130183241-A1 | PEPTIDES THAT HOME TO TUMOR LYMPHATIC VASCULATURE AND METHODS OF USING SAME | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2013-07-18 | — | — | US | disclosed |
| US-8329859-B2 | Peptides that home to tumor lymphatic vasculature and methods of using same | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-12-11 | — | — | US | disclosed |
| US-20110165083-A1 | Peptides that home to tumor lymphatic vasculature and methods of using same | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2011-07-07 | — | — | US | disclosed |
| US-7671021-B2 | Peptides that home to tumor lymphatic vasculature and methods of using same | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-03-02 | — | — | US | disclosed |
| US-20070149444-A1 | Peptides that home to tumor lymphatic vasculature and methods of using same | THE BURNHAM INSTITUTE (US) | 2007-06-28 | — | — | US | disclosed |