Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19014758 | 0.81 | LMNA (0.48) | TRPM8LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL19014677 | 0.81 | LMNA (0.48) | TRPM8LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL19014832 | 0.81 | LMNA (0.48) | TRPM8LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12559956 | 0.81 | CA12 (0.46) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL20306561 | 0.78 | TAS1R3 (0.36) | TRPM8LMNAGAACHRM3 | |
| SCHEMBL12159639 | 0.78 | BCHE (0.39) | ALDH1A1GAACHRM1 | |
| SCHEMBL2191290 | 0.77 | NOTUM (0.39) | TRPM8KMT2AGAATSHR | |
| SCHEMBL8558598 | 0.76 | IDO1 (0.53) | LMNAALDH1A1MEN1KMT2AGAA | |
| SCHEMBL172877 | 0.76 | SLC6A2 (0.38) | — | |
| SCHEMBL9722001 | 0.74 | IDO1 (0.55) | TRPM8LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10590057-B2 | Isotopic fluorination and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10590057-B2 | Isotopic fluorination and applications thereof | FTH1, SFXN3, SOD1 | TRPM8 4419/4885LMNA 1987/4885ALDH1A1 3943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.