Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 5/20 | 0.45 |
| ▸ | BDNF | P23560 | 3/20 | 0.45 |
| ▸ | PTN | P21246 | 2/20 | 0.45 |
| ▸ | BMP2 | P12643 | 3/20 | 0.41 |
| ▸ | VEGFA | P15692 | 3/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.41 |
| ▸ | SHH | Q15465 | 2/20 | 0.41 |
| ▸ | IFNG | P01579 | 2/20 | 0.40 |
| ▸ | FGF1 | P05230 | 1/20 | 0.40 |
| ▸ | FGF2 | P09038 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.39 |
| ▸ | CCL2 | P13500 | 2/20 | 0.38 |
| ▸ | PF4 | P02776 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | BMP6 | P22004 | 1/20 | 0.38 |
| ▸ | CCL11 | P51671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343934 | 0.94 | MDK (0.49) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL18312442 | 0.94 | MDK (0.49) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL21843061 | 0.91 | MDK (0.43) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL21843059 | 0.87 | MDK (0.45) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL18312774 | 0.85 | MDK (0.43) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL21843060 | 0.85 | BDNF (0.37) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL23343922 | 0.85 | MDK (0.47) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL18312274 | 0.85 | MDK (0.47) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL18313211 | 0.85 | LGALS8 (0.54) | MDKBDNFPTNBMP2VEGFA | |
| SCHEMBL21843053 | 0.85 | LGALS8 (0.54) | MDKBDNFPTNBMP2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10596272-B2 | Vaccines against Streptococcus pneumoniae serotype 5 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10596272-B2 | Vaccines against Streptococcus pneumoniae serotype 5 | FUT5, SPAG5, IL5 | MDK 3162/4885BDNF 2508/4885PTN 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.