SCHEMBL218438

SCHEMBL218438

Cc1ccc2c(c1C)[CH]c1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2A6 P11509 1/20 0.34
TDP2 O95551 1/20 0.34
NSD2 O96028 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PAX8 Q06710 1/20 0.34
POLB P06746 2/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 2/20 0.32
RECQL P46063 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
HBB P68871 1/20 0.32
SENP7 Q9BQF6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL216981 0.78 ACHE (0.39) TSHRCYP1A2CYP2A6ALDH1A1CYP3A4
SCHEMBL218324 0.78 KDM4E (0.33) CYP1A2CYP3A4NPSR1MEN1KMT2A
SCHEMBL217878 0.77 ALDH1A1 (0.36) TSHRCYP2A6ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL1036363 0.77 POLB (0.32) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL3064332 0.77 DCUN1D1 (0.40) TSHRCYP1A2CYP2A6TDP2ALDH1A1
SCHEMBL5146263 0.76 CA12 (0.31)
SCHEMBL9010064 0.73 ELANE (0.33) ALDH1A1ELANEMAPT
SCHEMBL1028158 0.72 ALDH1A1 (0.36) TSHRCYP1A2POLBALDH1A1CYP3A4
SCHEMBL218380 0.72 DHFR (0.44) TSHRCYP1A2CYP2A6ALDH1A1CYP3A4
SCHEMBL2959818 0.71 CYP1A2 (0.31) TSHRCYP1A2CYP2A6TDP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3937 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023058644-A9 COMPOUND, ORGANIC EL ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE 東レ株式会社 2024-07-18 WO claimed
EP-4401536-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2024-07-17 EP claimed
CN-114621171-B Organic compound with naphthalene anthracene derivative as core and application thereof 江苏三月科技股份有限公司 2024-07-12 CN claimed
CN-118324774-A Organic functional material developed by taking xanthone pentaheterocycle and derivative thereof as core and application of organic functional material in device 华南理工大学 2024-07-12 CN claimed
CN-118307502-A Organic compound, OLED (organic light-emitting diode) with organic compound and organic light-emitting device 浙江华显光电科技有限公司 2024-07-09 CN claimed
CN-113861041-B Compound and application thereof 北京鼎材科技有限公司 2024-07-09 CN claimed
CN-118307514-A Organic electroluminescent compound and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-07-09 CN claimed
CN-118307581-A Organic compound, OLED (organic light-emitting diode) with organic compound and organic light-emitting device 浙江华显光电科技有限公司 2024-07-09 CN claimed
CN-118291125-A Organic material composition and application thereof 宁波卢米蓝新材料有限公司 2024-07-05 CN claimed
CN-118290414-A Benzoxazole organic compound containing benzonaphthofuran and application thereof 宁波卢米蓝新材料有限公司 2024-07-05 CN claimed
EP-2076551-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND -OLEFINS SK Energy Co., Ltd. (KR) 2009-07-08 EP claimed
US-20090146555-A1 Heterocyclic compound and organic light emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2009-06-11 US claimed
WO-2008047957-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND α-OLEFINS SK ENERGY CO., LTD. (KR) 2008-04-24 WO claimed
EP-1910427-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK Energy Co., Ltd. (KR) 2008-04-16 EP claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-20070135297-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND a-OLEFINS SK CORPORATION (KR) 2007-06-14 US claimed
WO-2007040294-A1 ARYLPHENOXY CATALYST SYSTEM FOR PRODUCING ETHYLENE HOMOPOLYMER OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFINS SK ENERGY CO., LTD. (KR) 2007-04-12 WO claimed
US-7186469-B2 Bathophenanthroline compound and EL device SONY CORPORATION (JP) 2007-03-06 US claimed
US-20070004586-A1 Arylphenoxy catalyst system for producing ethylene homopolymer or copolymers of ethylene and alpha-olefins SK CORPORATION (KR) 2007-01-04 US claimed
US-5627247-A COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US claimed