SCHEMBL9010064

SCHEMBL9010064

Cc1ccc2c(c1P(=O)(O)O)[CH]c1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33
PTK2B Q14289 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA5A P35218 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218438 0.73 TSHR (0.34) ELANEALDH1A1MAPT
SCHEMBL9010087 0.73 PTK2B (0.36) PTK2BRXFP1CA2CA4CA5A
SCHEMBL3883001 0.70 ELANE (0.38) ELANECA2CA4CA5AALDH1A1
SCHEMBL1552134 0.70 TSHR (0.40) PTK2BRXFP1CA2CA4CA5A
SCHEMBL31031192 0.70 TSHR (0.40) PTK2BRXFP1CA2CA4CA5A
SCHEMBL3892091 0.69 MYC (0.41) ELANECA2CA4CA5AALDH1A1
SCHEMBL216981 0.69 ACHE (0.39) CA2ALDH1A1
SCHEMBL217878 0.68 ALDH1A1 (0.36) ELANEALDH1A1MAPT
SCHEMBL3064332 0.67 DCUN1D1 (0.40) ALDH1A1MAPT
SCHEMBL27469812 0.67 ACHE (0.38) CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0741145-A1 Olefin polymerization catalyst and process for producing polyolefin using the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-11-06 EP disclosed