SCHEMBL2184403

SCHEMBL2184403

CCCOC(=O)NC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPK1 P28482 1/20 0.47
MAPT P10636 2/20 0.46
RAB9A P51151 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ACHE P22303 8/20 0.42
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
EPHX1 P07099 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CRBN Q96SW2 1/20 0.39
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4451188 0.87 RAB9A (0.61) SMN1; SMN2ALDH1A1MAPTRAB9ANPSR1
SCHEMBL2912153 0.85 ACHE (0.48) SMN1; SMN2ALDH1A1MAPK1ACHEKDM4E
SCHEMBL1607872 0.85 CRBN (0.39) SMN1; SMN2ALDH1A1MAPK1MAPTRAB9A
SCHEMBL6687894 0.85 EPHX1 (0.60) MAPTRAB9ANPSR1ACHEEPHX1
SCHEMBL2185689 0.84 EPHX1 (0.63) MAPTRAB9ANPSR1ACHEEPHX1
SCHEMBL2185919 0.84 EPHX1 (0.63) MAPTRAB9ANPSR1ACHEEPHX1
SCHEMBL2184904 0.84 EPHX1 (0.63) MAPTRAB9ANPSR1ACHEEPHX1
SCHEMBL2189540 0.84 EPHX1 (0.63) MAPTRAB9ANPSR1ACHEEPHX1
SCHEMBL2184501 0.84 EPHX1 (0.63) MAPTRAB9ANPSR1ACHEEPHX1
SCHEMBL2185950 0.84 EPHX1 (0.63) MAPTRAB9ANPSR1ACHEEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
CN-1886490-B Lubricating oil additive and lubricating oil composition NIPPON OIL CORP 2011-04-27 CN disclosed
CN-1886490-A Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2006-12-27 CN disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed
EP-0588785-A1 UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1994-03-30 EP disclosed
EP-0588785-A4 UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS. ABBOTT LAB (US) 1991-12-30 EP disclosed
WO-1990012008-A1 UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1990-10-18 WO disclosed
US-4226779-A HEAT TREATMENT, NITROGEN COMPOUND, LIQUID PRODUCT NIPPON ZEON CO. LTD. (JP) 1980-10-07 US disclosed