SCHEMBL2184468

SCHEMBL2184468

CC(C)CCOC(=O)NC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 5/20 0.42
CHRNA4 P43681 5/20 0.42
CHRNB4 P30926 4/20 0.40
CHRNA3 P32297 4/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
PKM P14618 2/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HTT P42858 1/20 0.37
CYP19A1 P11511 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7955264 0.86 CHRNB2 (0.41) CHRNB2CHRNA4CHRNB4CHRNA3MAPK1
SCHEMBL10619780 0.85 EPHX1 (0.41) MAPTRAB9ANPSR1
SCHEMBL1607872 0.80 CRBN (0.39) CHRNB2CHRNA4CA2CA9MAPK1
SCHEMBL28220066 0.79 SMN1; SMN2 (0.43) MAPK1HSD17B10ALDH1A1KDM4EMAPT
SCHEMBL2184403 0.77 SMN1; SMN2 (0.47) MAPK1ALDH1A1KDM4EKMT2AMAPT
SCHEMBL20718324 0.77 CHRNB2 (0.66) CHRNB2CHRNA4CHRNB4CHRNA3CA12
SCHEMBL224100 0.76
SCHEMBL12787080 0.75 CHRNB2 (0.44) CHRNB2CHRNA4CHRNB4CHRNA3CA12
SCHEMBL21176408 0.74 EPHX1 (0.47) ALDH1A1MAPTRAB9ANPSR1
SCHEMBL8343978 0.74 ACHE (0.44) CHRNB2CHRNA4CHRNB4CHRNA3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481467-B2 low friction properties and anti-wear properties and are excellent in long drain capability; reaction product of a nitrogen-containing compound such as a semicarbazide and an organic metal compound to form an oil soluble metal complex NIPPON OIL CORPORATION (JP) 2013-07-09 US disclosed
EP-2343354-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
EP-2343355-A1 Lubricating oil additive and lubricating oil composition Nippon Oil Corporation (JP) 2011-07-13 EP disclosed
CN-1886490-B Lubricating oil additive and lubricating oil composition NIPPON OIL CORP 2011-04-27 CN disclosed
CN-1886490-A Lubricating oil additive and lubricating oil composition NIPPON OIL CORP (JP) 2006-12-27 CN disclosed
US-20060172900-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORPORATION (JP) 2006-08-03 US disclosed
EP-1686167-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-08-02 EP disclosed
US-4226779-A HEAT TREATMENT, NITROGEN COMPOUND, LIQUID PRODUCT NIPPON ZEON CO. LTD. (JP) 1980-10-07 US disclosed