Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411217 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL3995216 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL2184468 | 0.79 | CHRNB2 (0.42) | ALDH1A1KDM4EMAPTMAPK1HSD17B10 | |
| SCHEMBL9990175 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL13773178 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL2995503 | 0.77 | — | — | |
| SCHEMBL5161738 | 0.77 | ALDH1A1 (0.44) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL16922403 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL9074125 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT | |
| SCHEMBL8299466 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2TSHRALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137783-A | Production of in situ crosslinkable polyisobutylene-polyurethane nanofibers and coatings | 心脏起搏器股份公司 | 2018-06-08 | — | — | CN | claimed |