Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844848 | 0.86 | PARP1 (0.49) | BCHENPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL21844826 | 0.84 | NPC1 (0.51) | BCHENPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL1696476 | 0.81 | NPC1 (0.58) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL21844908 | 0.81 | KDM1A (0.48) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL15676754 | 0.79 | NPC1 (0.61) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL21844862 | 0.76 | MEN1 (0.59) | RAB9ATP53SMN1; SMN2KDM4ETSHR | |
| SCHEMBL17664548 | 0.75 | NPC1 (0.59) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL19157165 | 0.74 | BCHE (0.59) | BCHENPC1RAB9ATSHRMEN1 | |
| SCHEMBL12700261 | 0.74 | TP53 (0.75) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL1690509 | 0.73 | NPC1 (0.57) | NPC1RAB9ATP53SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |