Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20084043 | 0.90 | SMN1; SMN2 (0.47) | TP53SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL21844909 | 0.85 | KMT2A (0.40) | KDM1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL20084044 | 0.83 | MAOB (0.44) | KDM1ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL21844906 | 0.81 | BCHE (0.49) | KDM1ATP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1696476 | 0.76 | NPC1 (0.58) | KDM1ATP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21844860 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AKDM4ETSHR | |
| SCHEMBL19157637 | 0.74 | NPC1 (0.50) | TP53SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL15676754 | 0.74 | NPC1 (0.61) | KDM1ATP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21844862 | 0.73 | MEN1 (0.59) | TP53SMN1; SMN2RAB9AKDM4ETSHR | |
| SCHEMBL17664548 | 0.72 | NPC1 (0.59) | KDM1ATP53SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |