Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21844826 | 0.86 | NPC1 (0.51) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL21844906 | 0.86 | BCHE (0.49) | KDRMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL21844896 | 0.80 | PARP1 (0.49) | PARP1KDRMEN1KMT2ARAB9A | |
| SCHEMBL19157362 | 0.74 | LMNA (0.54) | MEN1KMT2ARAB9ANPC1CASP3 | |
| SCHEMBL4248100 | 0.73 | KCNK3 (0.69) | MEN1KMT2ARAB9ANPC1CASP3 | |
| SCHEMBL20084043 | 0.73 | SMN1; SMN2 (0.47) | PARP1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL19157150 | 0.73 | PARP1 (0.51) | PARP1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL19157165 | 0.72 | BCHE (0.59) | MEN1KMT2ARAB9ANPC1HPGD | |
| SCHEMBL21844862 | 0.72 | MEN1 (0.59) | MEN1KMT2ARAB9APOLBLMNA | |
| SCHEMBL7748140 | 0.72 | NPC1 (0.73) | MEN1KMT2ARAB9ANPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |