Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083959 | 0.83 | LMNA (0.48) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21844941 | 0.77 | GBA1 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL15276918 | 0.73 | KMT2A (0.49) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21844938 | 0.72 | LMNA (0.50) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL18948579 | 0.67 | KMT2A (0.40) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL15276912 | 0.67 | SIRT2 (0.48) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15276967 | 0.67 | LMNA (0.47) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21844861 | 0.65 | PSEN1 (0.38) | ALDH1A1MAPTSMN1; SMN2HTTMEN1 | |
| SCHEMBL19157362 | 0.63 | LMNA (0.54) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL15276917 | 0.62 | LMNA (0.52) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |