Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | AURKAIP1 | Q9NWT8 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076746 | 0.81 | MEN1 (0.51) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL21844941 | 0.74 | GBA1 (0.43) | KMT2AMEN1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL18948558 | 0.70 | GSTO1 (0.46) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL21844861 | 0.70 | PSEN1 (0.38) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL21844937 | 0.68 | GSTO1 (0.39) | KMT2AMEN1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL2852904 | 0.68 | KMT2A (0.56) | KMT2AMEN1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL2224740 | 0.68 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL21844939 | 0.67 | ALDH1A1 (0.40) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL15076755 | 0.67 | HTR2B (0.51) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL15276893 | 0.67 | SIRT2 (0.60) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676747-B2 | Hepatitis B antiviral agents | NOVIRA THERAPEUTICS, INC. (US) | 2017-06-13 | — | — | US | disclosed |