Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076671 | 0.82 | RAB9A (0.55) | KMT2AMEN1HTTTSHRLMNA | |
| SCHEMBL21844939 | 0.77 | ALDH1A1 (0.40) | GBA1KMT2AMEN1HTTKDM4E | |
| SCHEMBL18948558 | 0.74 | GSTO1 (0.46) | KMT2AMEN1HTTKDM4ETSHR | |
| SCHEMBL18948579 | 0.74 | KMT2A (0.40) | GBA1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL15276917 | 0.73 | LMNA (0.52) | KMT2AMEN1HTTTSHRLMNA | |
| SCHEMBL15276918 | 0.71 | KMT2A (0.49) | KMT2AMEN1HTTLMNAMAPT | |
| SCHEMBL21844846 | 0.69 | MDM2 (0.42) | KMT2AMEN1HTTKDM4ETSHR | |
| SCHEMBL22062424 | 0.69 | HTR2B (0.49) | GBA1ALDH1A1 | |
| SCHEMBL15076676 | 0.69 | LMNA (0.52) | KMT2AMEN1HTTTSHRLMNA | |
| SCHEMBL20131072 | 0.68 | HTR2B (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |