Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.38 |
| ▸ | SPPL2A | Q8TCT8 | 5/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083990 | 0.79 | LMNA (0.49) | MEN1KMT2AMAPTRECQLTP53 | |
| SCHEMBL15276910 | 0.71 | HTR2B (0.56) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL21844860 | 0.71 | SMN1; SMN2 (0.58) | MEN1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL18948579 | 0.70 | KMT2A (0.40) | MEN1KMT2AMAPTRECQLKDM4E | |
| SCHEMBL15276906 | 0.69 | SIRT2 (0.52) | MEN1KMT2APKMMAPTSMN1; SMN2 | |
| SCHEMBL21844939 | 0.65 | ALDH1A1 (0.40) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL15276909 | 0.65 | RAB9A (0.50) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15276907 | 0.65 | SLC6A9 (0.46) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15276904 | 0.64 | MAPT (0.52) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL700255 | 0.64 | CCR1 (0.39) | ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3312160-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2020-03-18 | — | — | EP | disclosed |