Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748098 | 0.79 | ALDH1A1 (0.66) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| Iodide SCHEMBL1770191 | 0.78 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL13050515 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDMAPTPKM | |
| Hydrochloric Acid SCHEMBL28519025 | 0.76 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2615997 | 0.76 | LMNA (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5432001 | 0.76 | PDPK1 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL316414 | 0.76 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14000914 | 0.76 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL534640 | 0.76 | ALDH1A1 (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2623678 | 0.76 | SMN1; SMN2 (0.61) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-B1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2020-03-18 | — | — | EP | disclosed |