Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23452850 | 0.80 | KDM4E (0.55) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL28726329 | 0.74 | SORT1 (0.41) | — | |
| SCHEMBL21845392 | 0.71 | BCHE (0.35) | — | |
| SCHEMBL21845603 | 0.71 | CPB1 (0.40) | MEN1KMT2AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL17632635 | 0.68 | UCHL1 (0.53) | — | |
| SCHEMBL28356454 | 0.67 | NPC1 (0.46) | NPC1RAB9A | |
| SCHEMBL21845534 | 0.67 | CYP1A2 (0.47) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20205013 | 0.66 | — | — | |
| SCHEMBL23451270 | 0.64 | MGLL (0.43) | NPC1RAB9AMAPT | |
| SCHEMBL28103065 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-B1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2020-03-18 | — | — | EP | disclosed |