SCHEMBL2184695

SCHEMBL2184695

C[Si](OP(=O)(O)O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.30
BLM P54132 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL437818 0.69
SCHEMBL27097413 0.69 FDPS (0.39) FDPSBLMTDP1
SCHEMBL28417042 0.67 FDPS (0.37) FDPSBLMTDP1
SCHEMBL22973786 0.67 LMNA (0.33) FDPSBLMTDP1
SCHEMBL4230060 0.66
SCHEMBL27183178 0.63 PGK1 (0.30)
SCHEMBL17447253 0.62 FDPS (0.44) FDPSBLMTDP1
SCHEMBL4236870 0.62 SMPD1 (0.31)
SCHEMBL8032121 0.62 FDPS (0.32) FDPSBLMTDP1
SCHEMBL28085049 0.62 LPAR3 (0.33) FDPSBLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110220844-A1 SULFONATE MODIFIED NANOCRYSTALS Life Technologies Corporation 2011-09-15 US claimed
EP-2342161-A2 SULFONATE MODIFIED NANOCRYSTALS Life Technologies Corporation (US) 2011-07-13 EP claimed
WO-2010040111-A2 SULFONATE MODIFIED NANOCRYSTALS Life Technologies Corporation (US) 2010-04-08 WO claimed