Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.34 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17828141 | 0.81 | POLB (0.42) | CYP1A2POLBSMN1; SMN2SREBF1SREBF2 | |
| SCHEMBL21863400 | 0.75 | UHRF1 (0.46) | CYP1A2SMN1; SMN2CYP2C9HTR1DHTR1B | |
| Water SCHEMBL28114124 | 0.71 | HRH4 (0.50) | CYP1A2POLBPROKR1 | |
| SCHEMBL21848985 | 0.70 | CYP2C9 (0.36) | CYP1A2SMN1; SMN2CYP2C9PRKCIALDH1A1 | |
| SCHEMBL9885020 | 0.69 | SIRT2 (0.47) | CYP1A2POLBSREBF1SREBF2ALDH1A1 | |
| SCHEMBL13562439 | 0.69 | HRH4 (0.57) | CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL16841256 | 0.69 | PIK3CA (0.43) | ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL218290 | 0.69 | NOS3 (0.61) | CYP1A2POLBSREBF1SREBF2PRKCI | |
| SCHEMBL31555358 | 0.69 | CYP1A2 (0.52) | CYP1A2POLBSREBF1SREBF2PRKCI | |
| SCHEMBL25532616 | 0.68 | MGLL (0.51) | CYP1A2POLBSMN1; SMN2CYP2C9QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102311-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | CYP1A2 767/4885POLB 2574/4885SMN1; SMN2 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.