Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 5/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185063 | 1.00 | L3MBTL1 (0.50) | L3MBTL1POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL14864228 | 0.85 | ALDH1A1 (0.44) | L3MBTL1POLBALDH1A1TERT | |
| SCHEMBL14864229 | 0.85 | ALDH1A1 (0.44) | L3MBTL1POLBALDH1A1TERT | |
| SCHEMBL28194957 | 0.84 | POLB (0.44) | L3MBTL1POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL28241784 | 0.84 | POLB (0.44) | L3MBTL1POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL28138449 | 0.84 | POLB (0.44) | L3MBTL1POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL7763371 | 0.82 | POLB (0.52) | L3MBTL1POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL23107172 | 0.81 | POLB (0.41) | L3MBTL1POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL7764756 | 0.81 | L3MBTL1 (0.50) | L3MBTL1POLBALDH1A1SPHK2SPHK1 | |
| SCHEMBL10002487 | 0.81 | POLB (0.50) | L3MBTL1POLBALDH1A1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2546242-B1 | Cannabinoid receptor ligands | ABBVIE INC (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-2457903-B1 | Cannabinoid receptor ligands | ABBVIE INC (US) | 2016-01-13 | — | — | EP | disclosed |
| US-8846730-B2 | Compounds as cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-09-30 | — | — | US | disclosed |
| EP-2546241-A1 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-2546242-A1 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2013-01-16 | — | — | EP | disclosed |
| EP-2457903-A1 | Cannabinoid receptor ligands | Abbott Laboratories (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2346843-A2 | SUBSTITUTED BENZAMIDES AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2011-07-27 | — | — | EP | disclosed |
| US-20100063022-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | US | disclosed |
| WO-2010028338-A2 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063022-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, NPY1R | L3MBTL1 3280/4885POLB 4677/4885ALDH1A1 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.