Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | FUT4 | P22083 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24895085 | 0.76 | CYP19A1 (0.48) | TPMTKDM4ECA12CA1CA2 | |
| SCHEMBL22289736 | 0.75 | PTPN1 (0.49) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL25981011 | 0.74 | CA12 (0.52) | TPMTKDM4ECA12CA1CA2 | |
| SCHEMBL28071758 | 0.73 | CA12 (0.67) | TPMTKDM4ECA12CA1CA2 | |
| SCHEMBL289536 | 0.71 | CA12 (0.64) | TPMTKDM4ECA12CA1CA2 | |
| SCHEMBL29555158 | 0.70 | KDM4E (0.64) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL71388 | 0.70 | KDM4E (0.64) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL850504 | 0.69 | TPMT (0.54) | TPMTKDM4ECA12CA1CA2 | |
| SCHEMBL3389826 | 0.69 | CDC25B (0.53) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL2186294 | 0.69 | SLC6A2 (0.54) | TPMTKDM4ECA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343279-B1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | KISSEI PHARMACEUTICAL (JP) | 2018-02-28 | — | — | EP | disclosed |
| CN-102186824-B | Fused-ring derivative and medical application of same | KISSEI PHARMACEUTICAL | 2014-03-12 | — | — | CN | disclosed |
| US-8263622-B2 | Fused-ring derivative and medical application of same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| CN-102186824-A | Fused-ring derivative and medical application of same | KISSEI PHARMACEUTICAL | 2011-09-14 | — | — | CN | disclosed |
| US-20110207935-A1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| EP-2343279-A1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2011-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207935-A1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | XDH, OAT, PON1 | TPMT 133/4885KDM4E 3834/4885CA12 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.