Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18961299 | 0.86 | CYP2A6 (0.58) | SLC6A2P2RY14CSNK2A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2184909 | 0.86 | PRMT1 (0.59) | SLC6A2P2RY14PRMT1CSNK2A1ALDH1A1 | |
| SCHEMBL27360806 | 0.85 | SLC6A2 (0.59) | SLC6A2P2RY14PRMT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13057644 | 0.84 | TPMT (0.47) | CSNK2A1ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL3420178 | 0.81 | SLC6A2 (0.56) | SLC6A2P2RY14PRMT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13057633 | 0.79 | BCL2L1 (0.56) | ALDH1A1SMN1; SMN2KDM4ECA12CA1 | |
| SCHEMBL4565723 | 0.79 | CASP6 (0.54) | SLC6A2P2RY14PRMT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12193501 | 0.79 | SLC6A2 (0.54) | SLC6A2P2RY14PRMT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7740699 | 0.78 | TRPA1 (0.54) | SLC6A2CSNK2A1ALDH1A1KDM4EMAPT | |
| SCHEMBL30277939 | 0.78 | TRPA1 (0.54) | SLC6A2CSNK2A1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287067-A1 | ANTIBACTERIAL COMPOUND | 주식회사 엘지화학 | 2023-01-19 | — | — | WO | disclosed |
| EP-2343279-B1 | FUSED-RING DERIVATIVE AND MEDICAL APPLICATION OF SAME | KISSEI PHARMACEUTICAL (JP) | 2018-02-28 | — | — | EP | disclosed |
| US-9745336-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2017-08-29 | — | — | US | disclosed |
| US-9745336-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2017-08-29 | — | — | US | disclosed |
| US-20140303003-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-10-09 | — | — | US | disclosed |
| US-20140303003-A1 | Fluorescent Dye Compounds, Conjugates and Uses Thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-10-09 | — | — | US | disclosed |
| US-8729267-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-05-20 | — | — | US | disclosed |
| US-8729267-B2 | Fluorescent dye compounds, conjugates and uses thereof | APPLIED BIOSYSTEMS, LLC (US) | 2014-05-20 | — | — | US | disclosed |
| CN-102186824-B | Fused-ring derivative and medical application of same | KISSEI PHARMACEUTICAL | 2014-03-12 | — | — | CN | disclosed |
| US-8669266-B2 | Quinoline-carboxamide derivatives as P2Y12 antagonists | SANOFI (FR) | 2014-03-11 | — | — | US | disclosed |
| EP-1265885-B1 | HYDROXYLATED/CARBOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1248778-B1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG IND OHIO INC (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6555028-B2 | Polymeric matrix compatibilized naphthopyrans | TRANSITIONS OPTICAL, INC. | 2003-04-29 | — | — | US | disclosed |
| EP-1265885-A2 | HYDROXYLATED/CARBOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1248778-A1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO 1,2-B] PYRAN COMPOUNDS | PPG Industries Ohio Inc. (US) | 2002-10-16 | — | — | EP | disclosed |
| US-6340766-B1 | PHOTOCHROMIC DYES ON SUBSTRATES LIKE GLASS WITH PROTECTIVE COATINGS | TRANSITION OPTICAL, INC. | 2002-01-22 | — | — | US | disclosed |
| US-20020007078-A1 | Novel substituted naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2002-01-17 | — | — | US | disclosed |
| US-20010025948-A1 | Polymeric matrix compatibilized naphthopyrans | TRANSITIONS OPTICAL LIMITED (IE) | 2001-10-04 | — | — | US | disclosed |
| WO-2001070719-A2 | HYDROXYLATED/CARBOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001051483-A1 | SUBSTITUTED PHOTOCHROMIC 2H-NAPHTHO [1,2-B] PYRAN COMPOUNDS | PPG INDUSTRIES OHIO, INC. (US) | 2001-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007078-A1 | Novel substituted naphthopyrans | CRYZ, NR2E3, UACA | SLC6A2 3713/4885P2RY14 497/4885PRMT1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.