Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361668 | 0.97 | CA2 (0.43) | CA2CA4CA5AESR1ESR2 | |
| Iodide SCHEMBL27336456 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| SCHEMBL6316218 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Iodide SCHEMBL3694471 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Water SCHEMBL7532602 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Hydrochloric Acid SCHEMBL996153 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| SCHEMBL10710709 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2582115 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Fluoride SCHEMBL11191593 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Carbon Monoxide SCHEMBL10931516 | 0.85 | CA2 (0.42) | CA2CA4CA5AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401937-A1 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND OLEFINS | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2022-12-22 | — | — | US | claimed |
| EP-4021913-A2 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND EPOXIDES | PTT Global Chemical Public Company Limited (TH) | 2022-07-06 | — | — | EP | claimed |
| EP-4021914-A2 | CO2 CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM COAND OLEFINS | PTT Global Chemical Public Company Limited (TH) | 2022-07-06 | — | — | EP | claimed |
| WO-2021066756-A2 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND OLEFINS | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2021-04-08 | — | — | WO | claimed |
| WO-2021066757-A2 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND EPOXIDES | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2021-04-08 | — | — | WO | claimed |
| EP-2342258-B1 | PURIFICATION OF POLYCARBONATES | NOVOMER INC (US) | 2015-11-11 | — | — | EP | claimed |
| US-8252891-B2 | Purification of polycarbonates | NOVOMER, INC. (US) | 2012-08-28 | — | — | US | claimed |
| US-20110201779-A1 | PURIFICATION OF POLYCARBONATES | NOVOMER, INC. (US) | 2011-08-18 | — | — | US | claimed |
| EP-2342258-A1 | PURIFICATION OF POLYCARBONATES | Novomer, Inc. (US) | 2011-07-13 | — | — | EP | claimed |
| WO-2010033703-A1 | PURIFICATION OF POLYCARBONATES | NOVOMER, INC. (US) | 2010-03-25 | — | — | WO | claimed |
| US-20220401937-A1 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND OLEFINS | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2022-12-22 | — | — | US | disclosed |
| EP-4021914-A2 | CO2 CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM COAND OLEFINS | PTT Global Chemical Public Company Limited (TH) | 2022-07-06 | — | — | EP | disclosed |
| EP-4021913-A2 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND EPOXIDES | PTT Global Chemical Public Company Limited (TH) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021066756-A2 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND OLEFINS | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2021-04-08 | — | — | WO | disclosed |
| WO-2021066757-A2 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND EPOXIDES | PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) | 2021-04-08 | — | — | WO | disclosed |
| EP-0120462-A1 | Accelerators for vulcanizing vinylidene fluoride elastomeric copolymers | Montedison S.p.A. (IT) | 1984-10-03 | — | — | EP | disclosed |
| US-4460709-A | Process for producing oxygen-containing organic compounds | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1984-07-17 | — | — | US | disclosed |
| EP-0085191-A1 | Continuous process for producing alcohols | UNION CARBIDE CORPORATION (US) | 1983-08-10 | — | — | EP | disclosed |
| EP-0084682-A1 | Process for producing alcohols | UNION CARBIDE CORPORATION (US) | 1983-08-03 | — | — | EP | disclosed |
| EP-0075937-A1 | Process for producing alcohols | UNION CARBIDE CORPORATION (US) | 1983-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220401937-A1 | CATALYST COMPOSITION FOR CYCLIC CARBONATE PRODUCTION FROM CO2 AND OLEFINS | CA3, CA2, CHN2 | SLC6A2 4023/4885CA2 2/4885CA4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.