Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.61 |
| ▸ | AR | P10275 | 4/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673342 | 0.92 | ESR1 (0.65) | ESR1ESR2ARHPGDHSD17B10 | |
| SCHEMBL11721914 | 0.91 | ESR1 (0.56) | ESR1ESR2ARSHBGCYP3A4 | |
| SCHEMBL7969173 | 0.89 | ESR1 (0.61) | ESR1ESR2ARCYP3A4ALDH1A1 | |
| SCHEMBL10909749 | 0.87 | ESR1 (0.69) | ESR1ESR2AR | |
| SCHEMBL14760222 | 0.87 | ESR1 (0.69) | ESR1ESR2AR | |
| SCHEMBL30374804 | 0.86 | ESR1 (0.54) | ESR1ESR2AR | |
| SCHEMBL2413116 | 0.86 | ESR1 (0.57) | ESR1ESR2ARSHBGCYP3A4 | |
| SCHEMBL30375402 | 0.84 | ESR1 (0.56) | ESR1ESR2ARCYP3A4ESRRG | |
| SCHEMBL29499835 | 0.84 | ESR1 (0.56) | ESR1ESR2AR | |
| SCHEMBL3967698 | 0.84 | SHBG (0.60) | ESR1ESR2ARSHBGCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530293-B2 | Polyamides and amidoamines derived from hydroxyalkylpolyamines: epoxy curing agents with improved properties | EVONIK OPERATIONS GMBH (DE) | 2022-12-20 | — | — | US | disclosed |
| US-20200308339-A2 | POLYAMIDES AND AMIDOAMINES DERIVED FROM HYROXYALKYLPOLYAMINES: EPOXY CURING AGENTS WITH IMPROVED PROPERTIES | EVONIK OPERATIONS GMBH (DE) | 2020-10-01 | — | — | US | disclosed |
| US-20200123312-A1 | POLYAMIDES AND AMIDOAMINES DERIVED FROM HYROXYALKYLPOLYAMINES: EPOXY CURING AGENTS WITH IMPROVED PROPERTIES | EVONIK OPERATIONS GMBH (DE) | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123312-A1 | POLYAMIDES AND AMIDOAMINES DERIVED FROM HYROXYALKYLPOLYAMINES: EPOXY CURING AGENTS WITH IMPROVED PROPERTIES | PAM, HNMT, NAAA | ESR1 1003/4885ESR2 1119/4885AR 1957/4885 |
| US-11530293-B2 | Polyamides and amidoamines derived from hydroxyalkylpolyamines: epoxy curing agents with improved properties | NAAA, PAM, PARG | ESR1 1534/4885ESR2 1591/4885AR 1962/4885 |
| US-20200308339-A2 | POLYAMIDES AND AMIDOAMINES DERIVED FROM HYROXYALKYLPOLYAMINES: EPOXY CURING AGENTS WITH IMPROVED PROPERTIES | PAM, HNMT, NAAA | ESR1 1003/4885ESR2 1119/4885AR 1957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.