Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL21854853 | 0.88 | HTR2C (0.47) | CTRB1CTSKCTSBCTSSNPSR1 | |
| Trifluoroacetic Acid SCHEMBL21854752 | 0.86 | F2 (0.46) | CTRB1NPSR1KMT2ATSHRHTR2C | |
| Trifluoroacetic Acid SCHEMBL21854670 | 0.86 | KDM4E (0.52) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL30253251 | 0.86 | HTR2C (0.46) | CTRB1CTSKCTSBCTSSNPSR1 | |
| Trifluoroacetic Acid SCHEMBL28969098 | 0.83 | PRCP (0.61) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL21854732 | 0.82 | HTR2C (0.51) | CTRB1CTSKCTSBCTSSNPSR1 | |
| SCHEMBL8707997 | 0.82 | NPSR1 (0.49) | CTRB1CTSKCTSBCTSSNPSR1 | |
| Trifluoroacetic Acid SCHEMBL957062 | 0.81 | HTR2C (0.59) | NPSR1KMT2AHTR2CMEN1PDK1 | |
| Trifluoroacetic Acid SCHEMBL956789 | 0.81 | HTR2C (0.59) | NPSR1KMT2AHTR2CMEN1PDK1 | |
| SCHEMBL6487292 | 0.79 | HTR2C (0.52) | CTRB1CTSKNPSR1PREPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081917-A1 | ΒETA-CATENIN AND B-CELL LYMPHOMA 9 (BCL9) INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |