Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178164 | 0.89 | MAPK1 (0.49) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL12408682 | 0.81 | L3MBTL1 (0.64) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6394883 | 0.80 | HPGD (0.63) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL2186195 | 0.80 | KDM4E (0.70) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL2927049 | 0.79 | HPGD (0.67) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL2179510 | 0.79 | MAPT (0.53) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL19072152 | 0.76 | SCN9A (0.63) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A | |
| SCHEMBL6395632 | 0.75 | MAPT (0.57) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL19180309 | 0.74 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL2178587 | 0.71 | KMT2A (0.59) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342191-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010030027-A1 | AROMATIC NITROGEN-CONTAINING 6-MEMBERED RING COMPOUNDS AND THEIR USE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-03-18 | — | — | WO | disclosed |