Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 5/20 | 0.47 |
| ▸ | NMBR | P28336 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388718 | 0.93 | MMP2 (0.51) | MMP2MMP3MAPTTP53LMNA | |
| SCHEMBL5388714 | 0.93 | MMP2 (0.51) | MMP2MMP3MAPTTP53LMNA | |
| SCHEMBL5388724 | 0.93 | MMP2 (0.51) | MMP2MMP3MAPTTP53LMNA | |
| SCHEMBL3125993 | 0.87 | ALOX15 (0.54) | MMP2MAPTLMNAMEN1KMT2A | |
| SCHEMBL6264591 | 0.87 | BCHE (0.56) | MMP2MMP3MAPTTP53LMNA | |
| SCHEMBL11588634 | 0.82 | ALOX15 (0.56) | MMP2BCHEMEN1KMT2AALOX15 | |
| SCHEMBL11588631 | 0.82 | ALOX15 (0.56) | MMP2BCHEMEN1KMT2AALOX15 | |
| SCHEMBL28378277 | 0.82 | ALOX15 (0.56) | MMP2BCHEMEN1KMT2AALOX15 | |
| SCHEMBL659943 | 0.81 | MAPT (0.57) | MMP2MMP3MAPTTP53LMNA | |
| SCHEMBL7076128 | 0.80 | MEN1 (0.62) | MMP2MMP3MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341924-A2 | METHODS OF TREATING HEPATITIS C VIRUS INFECTION | The J. David Gladstone Institutes (US) | 2011-07-13 | — | — | EP | disclosed |