Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.49 |
| ▸ | ITGAL | P20701 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11588634 | 0.91 | ALOX15 (0.56) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL28378277 | 0.91 | ALOX15 (0.56) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL11588631 | 0.91 | ALOX15 (0.56) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL2185643 | 0.87 | MMP2 (0.51) | ALOX15MEN1KMT2AMMP2SMN1; SMN2 | |
| SCHEMBL7766716 | 0.84 | NMBR (0.62) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL6244061 | 0.84 | MEN1 (0.62) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL8384762 | 0.84 | MEN1 (0.62) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL6245123 | 0.84 | MEN1 (0.62) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL6244059 | 0.84 | MEN1 (0.62) | ALOX15ACEMEN1KMT2AITGB2 | |
| SCHEMBL8384759 | 0.84 | MEN1 (0.62) | ALOX15ACEMEN1KMT2AITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039801-A2 | METHODS OF TREATING HEPATITIS C VIRUS INFECTION | THE J. DAVID GLADSTONE INSTITUTES (US) | 2010-04-08 | — | — | WO | disclosed |