Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858433 | 0.89 | HTT (0.34) | ALDH1A1HTTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL21858445 | 0.85 | NPSR1 (0.46) | ALDH1A1HTTCTSLCTSSCTSK | |
| SCHEMBL26440720 | 0.83 | PDE2A (0.34) | ALDH1A1HTT | |
| SCHEMBL18796398 | 0.81 | MAP4K4 (0.34) | ALDH1A1HTT | |
| SCHEMBL18796008 | 0.81 | ALDH1A1 (0.32) | ALDH1A1HTTNPSR1 | |
| SCHEMBL20104491 | 0.80 | KDM4E (0.38) | ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL21858430 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1HTTERN1 | |
| SCHEMBL12489258 | 0.80 | KMT2A (0.38) | CYP1A2KMT2AMEN1ATM | |
| SCHEMBL18796130 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL19901396 | 0.79 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-09 | — | — | US | disclosed |
| WO-2020079232-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | CBR3, CYP4X1, AOX1 | ALDH1A1 1754/4885HTT 3777/4885CTSL 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.