Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858424 | 0.89 | ALDH1A1 (0.33) | HTTALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL21858430 | 0.86 | SMN1; SMN2 (0.48) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL19472018 | 0.80 | MAPT (0.35) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL18796118 | 0.78 | LMNA (0.39) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL31576195 | 0.77 | LMNA (0.33) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL19484249 | 0.77 | LMNA (0.33) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL28630877 | 0.77 | LMNA (0.33) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL19484248 | 0.77 | SMN1; SMN2 (0.33) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL19484251 | 0.76 | LMNA (0.35) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL12488167 | 0.76 | EGLN1 (0.35) | HTTALDH1A1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-09 | — | — | US | disclosed |
| WO-2020079232-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | CBR3, CYP4X1, AOX1 | HTT 3777/4885ALDH1A1 1754/4885MAPT 3097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.