Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858424 | 0.85 | ALDH1A1 (0.33) | NPSR1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL18796251 | 0.82 | LMNA (0.39) | NPSR1LMNAKMT2AALDH1A1CTSL | |
| SCHEMBL26440720 | 0.80 | PDE2A (0.34) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL18796250 | 0.79 | L3MBTL1 (0.47) | LMNAKMT2AGAAALDH1A1HTT | |
| SCHEMBL18796108 | 0.79 | LMNA (0.32) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL18796008 | 0.78 | ALDH1A1 (0.32) | NPSR1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18796398 | 0.78 | MAP4K4 (0.34) | LMNAALDH1A1HTTSMN1; SMN2MAPT | |
| SCHEMBL18796110 | 0.78 | SLC6A4 (0.36) | LMNACTSLCTSSCTSKHTT | |
| SCHEMBL20104491 | 0.77 | KDM4E (0.38) | LMNAKMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL12489258 | 0.77 | KMT2A (0.38) | KMT2AGAACYP1A2ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-09 | — | — | US | disclosed |
| WO-2020079232-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210378240-A1 | OXETANYLPHENOXYQUINOLINES AND ANALOGUES | CBR3, CYP4X1, AOX1 | NPSR1 4500/4885LMNA 4265/4885KMT2A 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.