Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858860 | 0.78 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2AMAPTRXFP1 | |
| SCHEMBL12681304 | 0.71 | CCNK (0.43) | MEN1ALDH1A1KMT2ACCNKCDK12 | |
| SCHEMBL2053669 | 0.71 | CCNK (0.38) | MEN1ALDH1A1KMT2ACCNKCDK12 | |
| SCHEMBL2049844 | 0.70 | KDM4E (0.46) | MEN1ALDH1A1KMT2ACCNKCDK12 | |
| SCHEMBL12681327 | 0.67 | CCNK (0.39) | MEN1ALDH1A1KMT2ACCNKCDK12 | |
| SCHEMBL24526832 | 0.67 | — | — | |
| SCHEMBL20547561 | 0.66 | CCNK (0.39) | MEN1ALDH1A1KMT2ACCNKCDK12 | |
| SCHEMBL770898 | 0.65 | POLB (0.44) | MEN1KMT2AMAPTRXFP1POLB | |
| SCHEMBL17066883 | 0.65 | ALK (0.50) | MEN1ALDH1A1KMT2ACCNKCDK12 | |
| SCHEMBL28766747 | 0.65 | KMT2A (0.37) | MEN1ALDH1A1KMT2ACCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387964-A1 | HETEROARYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-16 | — | — | US | disclosed |
| CN-112888682-A | Heteroaryl aminoquinolines and analogs | 拜耳公司 | 2021-06-01 | — | — | CN | disclosed |
| WO-2020079167-A1 | HETEROARYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387964-A1 | HETEROARYLAMINOQUINOLINES AND ANALOGUES | PIK3C3, ERG28, CBR3 | MEN1 2984/4885ALDH1A1 2522/4885KMT2A 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.