Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 17/20 | 0.44 |
| ▸ | CA1 | P00915 | 11/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 7/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662361 | 0.91 | TP53 (0.52) | TP53CA2CA1OPRM1CA9 | |
| SCHEMBL27672980 | 0.84 | — | — | |
| SCHEMBL17495625 | 0.82 | TP53 (0.46) | TP53CA2CA1OPRM1 | |
| SCHEMBL222613 | 0.80 | TP53 (0.50) | TP53CA2CA1OPRM1CA9 | |
| SCHEMBL16240041 | 0.79 | CA2 (0.44) | TP53CA2CA1OPRM1CA9 | |
| SCHEMBL4807123 | 0.78 | TP53 (0.54) | TP53CA2CA1OPRM1 | |
| SCHEMBL8715933 | 0.77 | CA2 (0.43) | TP53CA2CA1CA9CA12 | |
| SCHEMBL28079461 | 0.76 | TP53 (0.42) | TP53CA2CA1OPRM1 | |
| SCHEMBL15562345 | 0.75 | CA2 (0.42) | TP53CA2CA1CA9CA12 | |
| SCHEMBL2707554 | 0.75 | GSR (0.43) | TP53CA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102159564-B | Arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-102159564-B | Arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LTD | 2014-06-18 | — | — | CN | disclosed |
| CN-102159564-B | Arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LTD | 2014-06-18 | — | — | CN | disclosed |
| EP-2346847-B1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-15 | — | — | EP | disclosed |
| US-8404720-B2 | Aryl sulfonamide amine compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2013-03-26 | — | — | US | disclosed |
| US-8404720-B2 | Aryl sulfonamide amine compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2013-03-26 | — | — | US | disclosed |
| US-8404720-B2 | Aryl sulfonamide amine compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2013-03-26 | — | — | US | disclosed |
| US-20120129816-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-05-24 | — | — | US | disclosed |
| US-20120129816-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2012-05-24 | — | — | US | disclosed |
| CN-102159564-A | Arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LTD | 2011-08-17 | — | — | CN | disclosed |
| CN-102159564-A | Arylsulfonamide compounds and their use as 5-HT6 ligands | SUVEN LIFE SCIENCES LTD | 2011-08-17 | — | — | CN | disclosed |
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| EP-2346847-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | Suven Life Sciences Limited (IN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010032258-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129816-A1 | ARYL SULFONAMIDE AMINE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | HTR6, HTR1A, HTR5A | TP53 4241/4885CA2 4069/4885CA1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.