Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17609585 | 0.72 | RAB9A (0.44) | ALDH1A1MEN1KMT2APKMLMNA | |
| SCHEMBL17609599 | 0.65 | TRPA1 (0.52) | PKMGAA | |
| SCHEMBL6212770 | 0.64 | DGAT1 (0.37) | NPC1MAPTDGAT1LMNAHSD17B10 | |
| SCHEMBL21527477 | 0.64 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2APKMCREBBP | |
| SCHEMBL29520372 | 0.64 | NPC1 (0.42) | ALDH1A1NPC1MAPTLMNAHSD17B10 | |
| SCHEMBL6259455 | 0.64 | NPC1 (0.42) | ALDH1A1NPC1MAPTLMNAHSD17B10 | |
| SCHEMBL17609509 | 0.64 | TRPA1 (0.45) | ALDH1A1PKMLMNAKDM4EGAA | |
| SCHEMBL16363910 | 0.62 | PNP (0.31) | DGAT1 | |
| SCHEMBL17609941 | 0.62 | TRPA1 (0.51) | ALDH1A1PKM | |
| SCHEMBL22075583 | 0.62 | DGAT1 (0.35) | ALDH1A1MEN1KMT2APKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |