Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079819 | 0.71 | SMN1; SMN2 (0.46) | LMNAALDH1A1 | |
| SCHEMBL9010481 | 0.68 | CYP2C19 (0.34) | ADORA2B | |
| SCHEMBL10280149 | 0.65 | TRPA1 (0.36) | HDAC6 | |
| SCHEMBL18656389 | 0.64 | APOBEC3A (0.41) | — | |
| SCHEMBL22902731 | 0.61 | APOBEC3A (0.37) | ALDH1A1 | |
| SCHEMBL21861648 | 0.61 | RAB9A (0.38) | LMNAKDM4EALDH1A1 | |
| SCHEMBL6092162 | 0.60 | APOBEC3A (0.36) | ALDH1A1 | |
| SCHEMBL19036600 | 0.59 | YTHDC1 (0.37) | — | |
| SCHEMBL19036512 | 0.58 | P2RY1 (0.37) | HDAC6 | |
| SCHEMBL19245922 | 0.58 | CYP11B2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193880-B1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | LILLY CO ELI (US) | 2020-03-25 | — | — | EP | disclosed |