Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.74 |
| ▸ | NAMPT | P43490 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 11/20 | 0.67 |
| ▸ | NPC1 | O15118 | 8/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664660 | 0.86 | PKM (0.74) | PKMNAMPTRAB9ANPC1MEN1 | |
| Water SCHEMBL11223699 | 0.82 | PKM (0.68) | PKMNAMPTRAB9ANPC1MEN1 | |
| SCHEMBL13270385 | 0.82 | NAMPT (1.00) | PKMNAMPTRAB9ANPC1PPARG | |
| SCHEMBL2515535 | 0.82 | NAMPT (0.59) | PKMNAMPTRAB9ANPC1MEN1 | |
| SCHEMBL1704235 | 0.81 | LMNA (0.54) | PKMNAMPTRAB9ANPC1MEN1 | |
| SCHEMBL9259634 | 0.81 | HPGD (0.63) | PKMNAMPTRAB9ANPC1MEN1 | |
| SCHEMBL4534169 | 0.81 | PKM (0.59) | PKMNAMPTRAB9ANPC1MEN1 | |
| SCHEMBL17660207 | 0.81 | PKM (0.67) | PKMNAMPTRAB9ANPC1MEN1 | |
| SCHEMBL30300673 | 0.81 | RAB9A (0.65) | PKMNAMPTRAB9ANPC1MEN1 | |
| SCHEMBL3640599 | 0.79 | DHODH (0.51) | PKMNAMPTRAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4679823-B2 | — | — | 2011-05-11 | — | — | JP | claimed |
| US-7381688-B2 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-03 | — | — | US | claimed |
| US-20060148886-A1 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | claimed |
| EP-1501820-B1 | METHYLTHIOPHENE CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2006-05-31 | — | — | EP | claimed |
| JP-2005529891-A | — | — | 2005-10-06 | — | — | JP | claimed |
| EP-1501820-A1 | METHYLTHIOPHENE CARBOXANILIDES | Bayer CropScience AG (DE) | 2005-02-02 | — | — | EP | claimed |
| WO-2003091240-A1 | METHYLTHIOPHENE CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | WO | claimed |
| JP-2011006432-A | METHYLTHIOPHENE CARBOXANILIDE | BAYER CROPSCIENCE AG | 2011-01-13 | — | — | JP | disclosed |
| US-7381688-B2 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-03 | — | — | US | disclosed |
| US-7381688-B2 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-03 | — | — | US | disclosed |
| US-7381688-B2 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AG (DE) | 2008-06-03 | — | — | US | disclosed |
| US-20060148886-A1 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | disclosed |
| US-20060148886-A1 | Methylthiophene carboxanilides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-06 | — | — | US | disclosed |
| EP-1501820-B1 | METHYLTHIOPHENE CARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2006-05-31 | — | — | EP | disclosed |
| EP-1501820-A1 | METHYLTHIOPHENE CARBOXANILIDES | Bayer CropScience AG (DE) | 2005-02-02 | — | — | EP | disclosed |
| EP-1501820-A1 | METHYLTHIOPHENE CARBOXANILIDES | Bayer CropScience AG (DE) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091240-A1 | METHYLTHIOPHENE CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003091240-A1 | METHYLTHIOPHENE CARBOXANILIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-11-06 | — | — | WO | disclosed |
| US-4097265-A | 3,5-Dimethyl-2-thienylcarboxanilide and 3,5-dimethyl-2-thienyl-(N-haloalkylthiocarboxanilide) herbicides | CHEVRON RESEARCH COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-3948633-A | 3,5-Dimethyl-2-thienylcarboxanilide and 3,5-dimethyl-2-thienyl-(N-haloalkylthiocarboxanilide) herbicides | CHEVRON RESEARCH COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148886-A1 | Methylthiophene carboxanilides | TRMT1, MRPL21, MCRS1 | PKM 1796/4885NAMPT 1813/4885RAB9A 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.