Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16202001 | 0.81 | CYP1A2 (0.48) | MAPTHTTCYP1A2ACHEMGLL | |
| SCHEMBL16202014 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTACHEMGLLADORA3 | |
| SCHEMBL21849282 | 0.80 | NOTUM (0.51) | NOTUMFGFR1ALDH1A1MAPTNPC1 | |
| SCHEMBL21849777 | 0.80 | NOTUM (0.48) | NOTUMFGFR1ALDH1A1MAPTNPC1 | |
| SCHEMBL21531873 | 0.78 | MAPK1 (0.48) | NOTUMFGFR1ALDH1A1MAPTNPC1 | |
| SCHEMBL21863282 | 0.78 | KEAP1 (0.47) | NOTUMACHEMGLLPI4KAPI4K2B | |
| SCHEMBL7127572 | 0.78 | MAPT (0.49) | FGFR1ALDH1A1MAPTCYP1A2TP53 | |
| SCHEMBL30186345 | 0.78 | FGFR1 (0.44) | FGFR1ALDH1A1MAPTACHETP53 | |
| SCHEMBL16202012 | 0.78 | NOTUM (0.47) | NOTUMFGFR1ALDH1A1MAPTNPC1 | |
| SCHEMBL21816160 | 0.77 | MAPT (0.58) | NOTUMALDH1A1MAPTMGLLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020065614-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-02 | — | — | WO | disclosed |