Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 4/20 | 0.33 |
| ▸ | FNTB | P49356 | 4/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865619 | 0.89 | AHCY (0.40) | AHCYALDH1A1LMNAMEN1HTT | |
| SCHEMBL21865383 | 0.84 | AHCY (0.41) | AHCYALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL21865632 | 0.83 | PSEN1 (0.45) | AHCY | |
| SCHEMBL21865385 | 0.83 | AHCY (0.40) | AHCYALDH1A1AAK1NPC1HPGD | |
| SCHEMBL28364266 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL21865761 | 0.82 | AHCY (0.40) | AHCYALDH1A1HTTNPC1HPGD | |
| SCHEMBL21865570 | 0.82 | AHCY (0.40) | AHCYALDH1A1MEN1HTTKMT2A | |
| SCHEMBL21865558 | 0.80 | ABL1 (0.40) | AHCYALDH1A1MEN1HTTKMT2A | |
| SCHEMBL21865672 | 0.80 | ALDH1A1 (0.42) | AHCYALDH1A1LMNAMEN1HTT | |
| SCHEMBL29835255 | 0.80 | ALDH1A1 (0.42) | AHCYALDH1A1LMNAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |