Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865387 | 0.83 | ALDH1A1 (0.46) | AHCYALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL21865562 | 0.83 | ALDH1A1 (0.41) | AHCYALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL21865672 | 0.82 | ALDH1A1 (0.42) | AHCYALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL29835255 | 0.82 | ALDH1A1 (0.42) | AHCYALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL29835216 | 0.81 | MAPT (0.50) | AHCYALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL21865761 | 0.80 | AHCY (0.40) | AHCYALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL21865620 | 0.79 | AHCY (0.41) | AHCYALDH1A1MAPTL3MBTL1IDO1 | |
| SCHEMBL17930966 | 0.76 | IDO1 (0.46) | ALDH1A1HTTMAPTIDO1NPSR1 | |
| SCHEMBL1308821 | 0.73 | NPSR1 (0.52) | ALDH1A1HTTMAPTL3MBTL1NPSR1 | |
| SCHEMBL21865632 | 0.72 | PSEN1 (0.45) | AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |