Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.38 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.37 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865562 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKDM4EAHCY | |
| SCHEMBL21865673 | 0.83 | AHCY (0.40) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL21865672 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EAHCY | |
| SCHEMBL29835255 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EAHCY | |
| SCHEMBL29835216 | 0.82 | MAPT (0.50) | ALDH1A1SMN1; SMN2AHCYMAPTHTT | |
| SCHEMBL21865570 | 0.79 | AHCY (0.40) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL15635741 | 0.75 | KDM4E (0.63) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6113658 | 0.74 | KDM4E (0.58) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL28371791 | 0.72 | CYP3A4 (0.44) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL21865558 | 0.72 | ABL1 (0.40) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |