Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21865387 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HTTMAPTL3MBTL1KDM4E | |
| SCHEMBL21865673 | 0.83 | AHCY (0.40) | ALDH1A1HTTMAPTL3MBTL1KDM4E | |
| SCHEMBL29835255 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HTTMAPTL3MBTL1KDM4E | |
| SCHEMBL21865672 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HTTMAPTL3MBTL1KDM4E | |
| SCHEMBL29835216 | 0.81 | MAPT (0.50) | ALDH1A1HTTMAPTL3MBTL1AHCY | |
| SCHEMBL21865558 | 0.80 | ABL1 (0.40) | ALDH1A1HTTKDM4EGLAGAA | |
| SCHEMBL15636023 | 0.77 | ABL1 (0.54) | ALDH1A1HTTMAPTL3MBTL1KDM4E | |
| SCHEMBL19545793 | 0.76 | STK17B (0.47) | ALDH1A1HTTMAPTKDM4EGLA | |
| SCHEMBL3531700 | 0.75 | ATR (0.53) | ALDH1A1HTTMAPTKDM4EGLA | |
| SCHEMBL29835191 | 0.75 | ABL1 (0.46) | ALDH1A1HTTMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052509-A1 | SULFONAMIDE COMPOUND SERVING AS SODIUM CHANNEL BLOCKER AND USES THEREOF | 成都康弘药业集团股份有限公司 | 2020-03-19 | — | — | WO | disclosed |