Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | MAP3K8 | P41279 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18311791 | 0.91 | ALOX5 (0.56) | ALOX5TDO2PTGIRMAPTMEN1 | |
| SCHEMBL15773283 | 0.91 | ALOX5 (0.55) | ALOX5TDO2PTGIRLIMK1ALDH1A1 | |
| SCHEMBL12960122 | 0.90 | ALOX5 (0.55) | ALOX5TDO2PTGIRLIMK1MAPT | |
| SCHEMBL24890121 | 0.89 | ALOX5 (0.57) | ALOX5TDO2PTGIRMAPTMEN1 | |
| SCHEMBL26366995 | 0.88 | LIMK1 (0.47) | ALOX5TDO2LIMK1MAPTMEN1 | |
| SCHEMBL17550955 | 0.88 | ALOX5 (0.52) | ALOX5TDO2PTGIRLIMK1PARP14 | |
| SCHEMBL17382556 | 0.87 | ALOX5 (0.58) | ALOX5TDO2PTGIRLIMK1PARP14 | |
| SCHEMBL24859106 | 0.87 | ALOX5 (0.43) | ALOX5TDO2PTGIRMAPTMEN1 | |
| SCHEMBL15615580 | 0.87 | ALOX5 (0.56) | ALOX5TDO2PTGIRLIMK1MAPT | |
| SCHEMBL23623297 | 0.86 | ALOX5 (0.55) | ALOX5LIMK1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807972-B2 | Indenotriphenylene-based amine derivative and organic electroluminescence device using the same | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2020-10-20 | — | — | US | disclosed |
| US-20200115369-A1 | INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807972-B2 | Indenotriphenylene-based amine derivative and organic electroluminescence device using the same | ICMT, INMT, PNMT | ALOX5 1299/4885TDO2 8/4885PTGIR 3497/4885 |
| US-20200115369-A1 | INDENOTRIPHENYLENE-BASED AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | ICMT, INMT, PNMT | ALOX5 1299/4885TDO2 8/4885PTGIR 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.