SCHEMBL21873276

SCHEMBL21873276

CSc1nc(-c2ccccc2O)nc(-c2cc3c4ccccc4ccc3c3ccccc23)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.68
▸ KMT2A Q03164 6/20 0.40
▸ MEN1 O00255 4/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ LMNA P02545 2/20 0.40
▸ HTT P42858 1/20 0.40
▸ HSP90AA1 P07900 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ TSHR P16473 5/20 0.38
▸ MAPT P10636 4/20 0.38
▸ HPGD P15428 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ ADORA3 P0DMS8 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ ADORA2A P29274 1/20 0.38
▸ ADORA2B P29275 1/20 0.38
▸ ADORA1 P30542 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21873277 0.91 MAPK1 (0.74) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL21873772 0.86 MAPK1 (0.49) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL21873275 0.86 MAPK1 (0.49) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL21873279 0.86 MAPK1 (0.49) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL24431818 0.84 MAPK1 (0.47) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL24431565 0.82 KMT2A (0.45) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL24431978 0.81 MAPK1 (0.43) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL21873280 0.79 MAPK1 (0.68) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL24431660 0.79 MAPT (0.52) MAPK1KMT2AMEN1KDM4ELMNA
SCHEMBL24431685 0.79 MAPT (0.52) MAPK1KMT2AMEN1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-19 — — US disclosed
WO-2020071695-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS 삼성디스플레이 주식회사 2020-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS CRY1, EPHB4, HTR3D MAPK1 4734/4885KMT2A 2009/4885MEN1 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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