SCHEMBL21873280

SCHEMBL21873280

CSc1nc(-c2ccccc2O)nc(-c2ccc3ccc4cccc5ccc2c3c45)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.68
▸ HSP90AA1 P07900 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ GUSB P08236 1/20 0.38
▸ KMT2A Q03164 5/20 0.38
▸ TSHR P16473 5/20 0.38
▸ MEN1 O00255 4/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ MAPT P10636 3/20 0.38
▸ ADORA2A P29274 2/20 0.38
▸ ADORA3 P0DMS8 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ ADORA2B P29275 1/20 0.38
▸ ADORA1 P30542 1/20 0.38
▸ HSD17B10 Q99714 4/20 0.36
▸ KDM4E B2RXH2 3/20 0.35
▸ LMNA P02545 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ HPGD P15428 4/20 0.35
▸ TDP1 Q9NUW8 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21873271 0.86 MAPK1 (0.49) MAPK1SMN1; SMN2GUSBKMT2ATSHR
SCHEMBL21873774 0.86 MAPK1 (0.49) MAPK1SMN1; SMN2GUSBKMT2ATSHR
SCHEMBL24431775 0.84 MAPK1 (0.47) MAPK1SMN1; SMN2GUSBKMT2ATSHR
SCHEMBL21873274 0.84 NPC1 (0.47) MAPK1SMN1; SMN2KMT2ATSHRMEN1
SCHEMBL24431684 0.82 MAPK1 (0.42) MAPK1SMN1; SMN2GUSBKMT2ATSHR
SCHEMBL24431657 0.81 MAPK1 (0.43) MAPK1KMT2ATSHRMEN1ALDH1A1
SCHEMBL21873276 0.79 MAPK1 (0.68) MAPK1HSP90AA1SMN1; SMN2KMT2ATSHR
SCHEMBL24431807 0.79 MAPT (0.49) MAPK1SMN1; SMN2GUSBKMT2ATSHR
SCHEMBL24431663 0.79 MAPT (0.49) MAPK1SMN1; SMN2GUSBKMT2ATSHR
SCHEMBL21873277 0.77 MAPK1 (0.74) MAPK1HSP90AA1SMN1; SMN2KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-19 — — US disclosed
WO-2020071695-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS 삼성디스플레이 주식회사 2020-04-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220158099-A1 DISPLAY APPARATUS AND LIGHT ABSORBER INCLUDED IN DISPLAY APPARATUS CRY1, EPHB4, HTR3D MAPK1 4734/4885HSP90AA1 828/4885SMN1; SMN2 2550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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