Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.48 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187577 | 0.87 | CSNK1E (0.47) | SCDCSNK1ECSNK1DCSNK1G3MTOR | |
| SCHEMBL2189066 | 0.82 | CSNK1E (0.69) | CSNK1ECSNK1DCSNK1G3MTORNPC1 | |
| SCHEMBL2187668 | 0.79 | KMT2A (0.48) | NPC1RAB9ASLC40A1GAAKMT2A | |
| SCHEMBL2187003 | 0.79 | CSNK1E (0.54) | SCDCSNK1ECSNK1DCSNK1G3MTOR | |
| SCHEMBL2187574 | 0.77 | GAA (0.44) | SCDNPC1RAB9APKMGAA | |
| SCHEMBL2187181 | 0.76 | CSNK1E (0.56) | CSNK1ECSNK1DCSNK1G3MTORNPC1 | |
| SCHEMBL2187404 | 0.74 | CSNK1E (0.65) | CSNK1ECSNK1DCSNK1G3MTORNPC1 | |
| SCHEMBL2186987 | 0.73 | CSNK1E (0.81) | CSNK1ECSNK1DCSNK1G3MTORNPC1 | |
| SCHEMBL2187583 | 0.72 | CSNK1E (0.43) | SCDCSNK1ECSNK1DCSNK1G3MTOR | |
| SCHEMBL2187302 | 0.71 | NPC1 (0.65) | CSNK1ECSNK1DCSNK1G3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |