Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 3/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187003 | 0.89 | CSNK1E (0.54) | CSNK1ECSNK1DHTR2BSCDCSNK1G3 | |
| SCHEMBL2187577 | 0.85 | CSNK1E (0.47) | CSNK1ECSNK1DHTR2BSCDCSNK1G3 | |
| SCHEMBL2187636 | 0.85 | HSD11B1 (0.45) | HSD11B1MGLLHCRTR1HCRTR2MAPK8 | |
| SCHEMBL2186531 | 0.82 | NFKB1 (0.41) | NFKB1NFKB2RELASMN1; SMN2NPC1 | |
| SCHEMBL2187771 | 0.80 | HTR2B (0.45) | HTR2BHSD11B1MGLLRBP4MAPK8 | |
| SCHEMBL2187132 | 0.80 | CSNK1E (0.54) | CSNK1ECSNK1DSCDCSNK1G3HSD11B1 | |
| SCHEMBL4294205 | 0.80 | HSD11B1 (0.52) | SCDHSD11B1MGLLHCRTR1HCRTR2 | |
| SCHEMBL2187530 | 0.79 | SMN1; SMN2 (0.47) | NFKB1NFKB2RELASMN1; SMN2NPC1 | |
| SCHEMBL28768418 | 0.77 | HSD11B1 (0.53) | HSD11B1MGLLHCRTR1HCRTR2MAPK8 | |
| SCHEMBL2189193 | 0.77 | CSNK1E (0.45) | CSNK1ECSNK1DCSNK1G3HSD11B1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343293-A1 | NOVEL PIPERIDIN-4-YL-THIAZOLE-CARBOXAMIDE ANALOGUES AS INHIBITORS OF T-CELL PROLIFERATION AND USES THEREOF | 4SC AG (DE) | 2011-07-13 | — | — | EP | disclosed |